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Pulmonary involvement in Sjögren’s syndrome - 17/06/09

Doi : RMR-04-2007-24-4-0761-8425-101019-20064258 

B. Crestani [1 et 6],

S. Schneider [5],

H. Adle-Biassette [2 et 6],

MP Debray [3 et 6],

M. Bonay [4 et 6],

M. Aubier [1 et 6]

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Abstract

Sjögren’s syndrome is a common auto-immune disease. The respiratory system is frequently involved with 10% of the patients developing a clinically significant lung disease. Respiratory disease may be the first manifestation of the syndrome. Beside interstitial lung diseases and bronchiolar disorders, cough is a very common symptom affecting about 50% of the patients in some studies, with limited therapeutic opportunities. Lung cysts, amyloid deposits, sometimes associated with lymphoma, have been recently described. Primary pulmonary lymphoma, usually from the MALT, is a very severe complication of the Sjögren’s syndrome.

Keywords: Connective tissue diseases , Lymphoma , Auto-immune disease , Pulmonary fibrosis , Sjögren


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© 2007 Elsevier Masson SAS. Tous droits réservés.
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Vol 24 - N° 4

P. 67-82 - avril 2007 Retour au numéro

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