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Five-year survival for lung cancer patients managed in general hospitals - 22/09/11

Doi : 10.1016/j.rmr.2008.07.001 
M. Grivaux a, M. Zureik b, L. Marsal c, B. Asselain d, M. Peureux e, J.-M. Chavaillon f, A. Prudhomme g, M. Carbonnelle h, E. Goarant i, B. Maury j, A. Bedossa k, F. Blanchon a,
a Service de pneumologie, hôpital de Meaux, 6-8, rue Saint-Fiacre, BP 218, 77104 Meaux cedex, France 
b Faculté de médecine X. Bichat, Inserm U700, Paris, France 
c Groupe hospitalier Diaconesses-Croix-Saint-Simon, Paris, France 
d Institut Curie, Paris, France 
e Hôpital du Havre, Le Havre, France 
f Hôpital d’Antibes, Antibes, France 
g Hôpital de Tarbes, Tarbes, France 
h Hôpital d’Épernay, Épernay, France 
i Hôpital de Saint-Malo, Saint-Malo, France 
j Hôpital de Cholet, Cholet, France 
k Hôpital de Lagny, Lagny, France 

Corresponding author.

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Summary

Introduction

In 2000, the college of pulmonologists of general hospitals undertook an epidemiological study (KBP-2000-CPHG) enrolling all new cases of histologically confirmed lung cancer managed in general hospitals. This paper reports the 5-year survival in these cases.

Methods

Vital status was available for 5447 out of 5667 patients included in the original study. The effect of different prognostic factors on mortality was assessed.

Results

At 5 years, 567 patients (10.4%) were still alive. Median survival for the 4880 (89.6%) deceased patients was 7 months. Univariate analysis identified age, smoking history, performance status, histological type and disease stage (TMN classification) as determinants of survival. For non-small cell lung cancer (n=4885) multivariate analysis identified five predictive factors for mortality – age, gender, histological type, performance status and stage.

Conclusions

Five-year survival in lung cancer continues to be poor. As the risk factors for poor outcome at the time of diagnosis are not modifiable and pending, the results of screening studies reduction in mortality must rest on primary prevention.

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Keywords : Small cell lung cancer, Non-small cell lung cancer, Primary lung cancer, General hospital, Survival


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© 2011  SPLF. Publicado por Elsevier Masson SAS. Todos los derechos reservados.
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Vol 28 - N° 7

P. e31-e38 - septembre 2011 Regresar al número
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